Hashimoto encephalopathy (HE) is an uncommon syndrome associated with Hashimoto thyroiditis Cantón A, de Fàbregas O, Tintoré M, et al. Request PDF on ResearchGate | On Jun 1, , Paloma Bacarizo and others published Encefalopatía de Hashimoto en un paciente de 20 años. CLINICAL/SCIENTIFIC NOTE. Hashimoto’s encephalopathy. Encefalite de Hashimoto. Renata Telles Rudge de AquinoI; Eduardo Genaro MutarelliII.

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It is associated with Hashimoto’s thyroiditis. This page was last edited on 16 Novemberat As mentioned above, autoantibodies to nashimoto enolase associated with Hashimoto’s encephalopathy have thus far been the most hypothesized mechanism of injury. Oligoclonal bands were absent. However, the role of those antibodies and their pathophysiology are unknown. MRI and cerebral encefaloatia are normal in the majority of cases 2.

Hashimoto’s disease and encephalopathy. From Wikipedia, the free encyclopedia. Views Read Edit View history. The correlation between anti-TPO and initial clinical progress observed was seen in some cases 8.

She was histrionic with disturbed thought. The mechanism of pathogenesis is not known but it has been hypothesized to be an autoimmune disorder, similar to Hashimoto’s thyroiditis as its name suggests.

We describe the case of a patient with Hashimoto’s encephalopathy who showed clinical manifestations similar to those of Creutzfeldt-Jakob disease. The prevalence has been estimated to be 2. The clinical presentation may suggest hashhimoto diagnosis of Creutzfeldt-Jakob disease.

How to cite this article. This improvement in the clinical presentation can be correlated to the complete resolution of hashi,oto electroencephalographic changes Fig 2B.

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SPECT can be normal but usually shows focal dd 8. Retrieved from ” https: Services on Demand Journal. Alopecia is encefakopatia with polyglandular autoimmunity. Symptoms sometimes resolve themselves within days to weeks, leaving a patient undiagnosed.

The most common findings are diffuse or generalized slowing or frontal intermittent rhythmic delta activity. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

The clinical manifestations associated with the presence of triphasic complexes in the EEG or the detection of the protein in the CSF make the diagnosis possible.

Some aspects warrant particular attention: Encephalomyelitis Acute disseminated Myalgic Meningoencephalitis. Antithyroid antibodies in the CSF: It was first described in It is sometimes referred to as a neuroendocrine disorder, although the condition’s relationship to the endocrine system is widely disputed.

All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. In some cases, Hashimoto’s encephalopathy can show rapidly progressive dementia, myoclonus, and electroencephalographic changes with periodic recurrence of the triphasic complexes similar to those of Creutzfeldt-Jakob disease, which makes a differential diagnosis essential to both pathologies 4.

Encefalopatia de Hashimoto

She was stable, ecefalopatia a hypothalamic dysfunction. However, the final diagnosis is obtained through a neuropathological exam 9. Hashimoto’s encephalopathy with clinical features similar to those of Creutzfeldt-Jakob disease. Diagnostic criteria are encephalopathy with elevated anti-thyroid antibodies in the absence of infection, tumour or alteration in the cerebral vascular system.

Hashimoto’s encephalitis as a differential diagnosis of Creutzfeldt-Jakob disease.

Hashimoto’s encephalopathy.

The presence rapidly progressive dementia, ataxia, myoclonus, and especially the presence of triphasic complexes in the EEG, make the diagnosis a probable one for Creutzfeldt-Jakob disease. Some symptoms may persist, such as tremors and loss of memory. In this period there was a regression of all signs and symptoms. This report emphasizes the importance of a differential diagnosis between the two pathologies. Rarity of encephalopathy associated with autoimmune thyroiditis: Hashimoto’s encephalopathy with clinical features similar to those of Creutzfeldt-Jacob disease.


Encephalitis Viral encephalitis Herpesviral encephalitis Limbic encephalitis Encephalitis lethargica Cavernous sinus thrombosis Brain abscess Amoebic.

Episodes of sinus tachycardia of bpm followed, with normal cardiac investigations. The presence of antithyroglobulin antibody Ac-anti-Tg was not detected. Eight years ago she developed hypothyroidism due to Hashimoto’s thyroiditis, and has been taking mcg levothyroxine daily.

The thyroid-stimulating hormone TSH was slightly elevated at 7.

CASE A female patient, years-old, Caucasian, widow, born in Rio de Janeiro, developed a clinical presentation of daily sadness, discouragement, decreased appetite, insomnia, and cognitive decline.

For many other patients, the encefwlopatia may result in ongoing problems with a variety of manifestations, often confusing clinicians due to the diffuse nature of symptoms. How to cite this article.

A possible vasculitic process has been shown in biopsy studies 7. Degenerative SA Friedreich’s ataxia Ataxia-telangiectasia. Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto’s encephalopathy. Evaluation of pathological anatomy revealed discrete venous or perivascular changes but not a true hashkmoto 4,8.